You can find a Molten Shrine POI during the Interlude after Act 4 in Path of Exile 2. Finding and completing this little point of interest will reward you with an increase of 5% to your Maximum Life. This is a permanent effect, too, so you should make sure to get it as soon as possible! Read on for all the details on how to complete the Molten Shrine.
How to Do Molten Shrine and Get +5% Maximum Life | Path of Exile 2

You can find the Molten Shrine point of interest at The Khari Crossing zone. That zone becomes available about halfway through the Interlude after Act 4 of the main campaign.
Note that, for some reason, this point of interest randomly shows as “completed” for some players. That’s even if they didn’t find the Maximum Life buff within! We recommend not trusting the World Map and double-checking, just in case.
Also, as usual with this game, the exact location of the Molten Shrine within The Khari Crossing isn’t set in stone. The zone’s layout is procedurally generated, so the point of interest location varies. That, of course, means that we, sadly, can’t tell you the exact location for it! Nonetheless, we can still help you by telling you what to look out for.

The actual location to look out for within The Khari Crossing is the Skullmaw Stairway. It looks like a massive skull with hands that are reaching out of the ground. This is also always near one of the checkpoints in the area. When you spot this cave, just walk into the skull’s mouth to move to the Molten Shrine zone proper.

Once inside, you’ll just need to reach the end of the short cave while killing the mobs along the way. Do so and you’ll eventually reach an altar with the Molten One’s Gift item on it. Finders keepers, so grab your well-deserved gift. You can consume it by using it from your inventory, giving you a permanent buff of +5% Maximum Life.
So, there you have it, that’s all you need to do to find the Molten Shrine POI in Path of Exile 2 and get more Maximum Life. Speaking of points of interest, we also have a guide on how to find the Dread Crab in Whakapanu Island.

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